Peptide LedgerEvidence · Safety · Status
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Peptide directory

A standardised record for every compound

Each profile follows the same template so compounds can be compared honestly: classification, mechanism, development stage, regulatory status, evidence level, safety, and references — with dated review.

9 of 9 profiles

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Semaglutide

Metabolic · Metabolic / endocrine

A long-acting GLP-1 receptor agonist approved for type 2 diabetes and, at higher doses, chronic weight management. One of the most extensively studied peptide medicines in modern endocrinology.

FDA-approved
GradeAStrong (multiple RCTs)
2026-08-14
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Tirzepatide

Metabolic · Metabolic / endocrine

A dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, with an expanding trial programme across cardiometabolic and sleep-related indications.

FDA-approved
GradeAStrong (multiple RCTs)
2026-08-13
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Retatrutide

Metabolic · Metabolic

An investigational triple agonist targeting GIP, GLP-1, and glucagon receptors. Phase 2 data have been reported; it is not an approved medicine anywhere.

Investigational
GradeBModerate (RCTs, limited scope)
2026-08-15
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BPC-157

Musculoskeletal · Musculoskeletal / gastrointestinal (proposed)

A synthetic pentadecapeptide widely marketed online and frequently discussed in injury-recovery contexts. Human evidence is very limited, and it is not an approved medicine.

Research use only
GradeDPreclinical only
2026-08-12
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TB-500

Musculoskeletal · Musculoskeletal / wound repair (proposed)

A synthetic fragment related to thymosin beta-4, marketed for tissue repair claims. Human clinical evidence is minimal, and it is prohibited in sport.

Research use only
GradeDPreclinical only
2026-08-10
Amber clinical-trial curves etched on smoked glass panels in warm gold light

Tesamorelin

Endocrine · Endocrine / metabolic

A growth-hormone-releasing hormone analogue approved for a narrow indication: reduction of excess abdominal fat in people with HIV-associated lipodystrophy.

FDA-approved
GradeBModerate (RCTs, limited scope)
2026-08-08
Translucent amber glass study of overlapping human organ systems

Ipamorelin

Endocrine · Endocrine (proposed)

A selective growth hormone secretagogue studied in early clinical work and later discontinued. It is not an approved medicine and is widely sold in unapproved channels.

Research use only
GradeCLimited (early human data)
2026-08-06
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CJC-1295

Endocrine · Endocrine (proposed)

A long-acting GHRH analogue investigated in early trials and never approved. Commonly marketed in unapproved channels alongside other secretagogues.

Research use only
GradeCLimited (early human data)
2026-08-04
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Copper peptides (GHK-Cu)

Cosmetic · Dermatology / cosmetic

A copper-binding tripeptide used in cosmetic skincare formulations. Regulated as a cosmetic ingredient rather than a medicine; evidence is mostly small studies and laboratory work.

Cosmetic
GradeCLimited (early human data)
2026-08-02

Editorial disclaimer

This site is educational and does not provide medical advice, dosing protocols, or treatment recommendations. Regulatory status and evidence strength differ sharply between compounds. A “research use only” label does not indicate that a product is appropriate for human use. Decisions about medicines belong with a qualified clinician.